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Gelum drops with positive effects in hepatic encephalopathy
Minimal hepatic encephalopathy (MHE) is one of the possible complications of cirrhosis of the liver. Now, in a study, a potassium-iron-phosphate-citrate complex (gelum drops) was tested for its effectiveness and safety in the therapy of MHE: with positive Results.
Minimal hepatic encephalopathy is a dysfunction of the central nervous system that is accompanied by neurological abnormalities. This can be explained by the deficient elimination of ammonia from the blood.
Gelum drops bind ammonia in the course of the passage of the intestine, i.e. that pathogenetic main factor of MHE. The ammonia is excreted with the drops and the body is relieved. So the result of the study.
In the placebo-controlled, double-blind clinical examination, 51 MHE patients were divided into two groups of the same size. They were given either gelum drops or placebo for 4 weeks. In a special syndrome test, the verum group showed significantly better results. 72% of the patients in the Gelum group were responders. In comparison, only 26.9% reacted positively in the placebo group. The quality of life also improved more in the Gelum group.
Appropriate dosage of gelum drops: Gelum drops are now approved for "liver cirrhosis with minimal hepatic encephalopathy". The dosage at MHE was set to three times 40 drops (3 x 2 ml). (Eur J Gastroenterol Hepatol. 2013 Mar; 25 (3): 352-8.)